American International Journal of Cancer Studies https://www.acseusa.org/journal/index.php/aijcs <p><strong>Aims and Scope</strong></p> <p>American International Journal of Cancer Studies is an international, double-blind peer-reviewed, open-access journal, published by the American Center of Science and Education. The journal is published in both print and online versions. The online version is free to access and download. The journal accepts article submissions by e-mail (<a href="mailto:aijcs@acseusa.org">aijcs@acseusa.org</a>).</p> <p>The subject areas include, but are not limited to the following fields:</p> <ul> <li>Cancer</li> <li>Clinical Trials</li> <li>Diagnosis and Treatment of Malignant Disease</li> <li>Genetics</li> <li>Molecular and Cellular Biology</li> <li>Palliative Care</li> <li>Pathophysiology</li> <li>Prevention</li> <li>Radiology</li> <li>Surgery</li> <li>Cancer cell biology</li> <li>Cancer genetics</li> <li>Cancer prevention</li> <li>Cancer therapy</li> <li>Carcinogenesis</li> <li>Clinical trials</li> <li>Diagnosis, cure and rehabilitation</li> <li>Diminish suffering from cancer</li> <li>Early detection and diagnosis</li> <li>Epidemiology</li> <li>Infectious causes of cancer</li> <li>Integrated systems and technology</li> <li>Microenvironment and immunology</li> <li>Molecular and cellular pathobiology</li> <li>Therapeutics and targets</li> <li>Treatment of human cancer</li> <li>Tumor and stem cell biology</li> <li>Tumor immunology</li> </ul> <p style="text-align: justify; color: #ff0000;"><em><strong>It is important to mention that all the works are showed without any kind of payment. All of them are published free from payments or taxes.</strong></em></p> <p><strong>Features</strong></p> <ul> <li><strong>First Review: </strong>The editor or Managing Editor decides whether the article fits within the journal’s aims and scope. Next, a check for the similarity rate is completed using Turnitin. Any manuscripts out of the journal’s scope or having plagiarism, including self-plagiarism, are rejected without peer-reviewed.</li> <li><strong>Peer Review:</strong> We use a double-blind system for peer review; both reviewers' and authors’ identities remain anonymous. The paper will be peer-reviewed by three experts; two reviewers from outside and one editor from the journal are typically involved in reviewing a submission. The review process may take 5-6 weeks.</li> <li><strong>DOIs at the Article Level: </strong>Each paper published in American International Journal of Cancer Studies is assigned a <a href="https://www.doi.org/">DOI</a> number, <a href="https://www.doi.org/">Click HERE</a> to know what is DOI (Digital Object Identifier).</li> <li><strong>High Visibility: </strong>American International Journal of Cancer Studies is indexed by Google Scholar.</li> <li>American Center of Science and Education takes the responsibility to enforce a rigorous peer-review together with strict ethical policies and standards to ensure adding high-quality scientific works to the field of scholarly publication. Unfortunately, cases of plagiarism, data falsification, inappropriate authorship credit, and the like, do arise. American Center of Science and Education takes such publishing ethics issues very seriously and our editors are trained to proceed in such cases with a zero-tolerance policy. To verify the originality of content submitted to our journals, we use Turnitin to check submissions against previous publications. American Center of Science and Education works with <a href="https://publons.com/about/home/">Publons</a> to provide reviewers with credit for their work.</li> </ul> American Center of Science and Education en-US American International Journal of Cancer Studies 2641-5658 OBESITY AND ITS RELATIONSHIP WITH CANCER: PART I OBESITY https://www.acseusa.org/journal/index.php/aijcs/article/view/214 <p><em>Cancer is a lethal disease and a strong barrier to a better life expectancy. It is the </em><em>first or second leading cause of death before the age of 70 years in 112 of 183 countries. </em><em>Its </em><em>incidence and mortality continue to grow rapidly all over the world. This manuscript is divided into four parts. Part I discusses obesity while Part II discusses the relationship between obesity and cancer. Part III and Part IV review the association of obesity on fifteen common cancers.</em></p> Shashi K. Agarwal Copyright (c) 2021 Shashi K. Agarwal https://creativecommons.org/licenses/by/4.0 2021-11-06 2021-11-06 3 1 1 13 10.46545/aijcs.v3i1.214 OBESITY AND ITS RELATIONSHIP WITH CANCER: PART II CANCER https://www.acseusa.org/journal/index.php/aijcs/article/view/217 <p><em>This four-part manuscript briefly reviews the association of obesity with cancer.</em><em> Part I discussed obesity while this (Part II) will discuss obesity and its impact on cancer. Part III and Part IV will review the association of obesity on fourteen common cancers.</em></p> Shashi K. Agarwal Copyright (c) 2021 Shashi K. Agarwal https://creativecommons.org/licenses/by/4.0 2021-11-06 2021-11-06 3 1 14 24 10.46545/aijcs.v3i1.217 OBESITY AND ITS RELATIONSHIP WITH CANCER: PART III https://www.acseusa.org/journal/index.php/aijcs/article/view/218 <p><em>Obesity and cancer has been discussed in the first two parts. This part (Part III) deals with six cancers, namely those involving the breast, colorectal tissues, esophagus, stomach. gall bladder, and liver. Their relationship with obesity is discussed. Part IV will look at endometrial, ovarian, pancreatic, prostate, renal, thyroid and lung carcinomas. Meningioma and multiple myeloma are also discussed.</em></p> Shashi K. Agarwal Copyright (c) 2021 Shashi K. Agarwal https://creativecommons.org/licenses/by/4.0 2021-11-06 2021-11-06 3 1 25 36 10.46545/aijcs.v3i1.218 OBESITY AND ITS RELATIONSHIP WITH CANCER: PART IV https://www.acseusa.org/journal/index.php/aijcs/article/view/219 <p><em>Part I thru III discussed obesity, its general relationship with cancer and its specific impact on </em><em>six cancers, namely those involving the breast, colorectal tissues, esophagus, stomach. gall bladder, and liver. This part (Part IV) deals with obesity and its relationship with cancers of the endometrium, ovary, pancreas, prostate, kidneys, thyroid, and lung. Meningioma and multiple myeloma are also discussed.&nbsp; </em></p> Shashi K. Agarwal Copyright (c) 2021 Shashi K. Agarwal https://creativecommons.org/licenses/by/4.0 2021-11-06 2021-11-06 3 1 37 48 10.46545/aijcs.v3i1.219 HETEROTRANSPLANTATIONS AND GENOMIC IN CANCER RESEARCH https://www.acseusa.org/journal/index.php/aijcs/article/view/220 <p><em>We performed ,in 1975, the first heterotransplantation of invertebrate A.O in nude mouse, then a double heterotransplantation of human tumor and Axial organ next to this last one, always in nude mouse: The human tumor was rejected in 50% of observed cases.Some</em></p> <p><em>years later,&nbsp; we found that A.O cells exerted an induced and spontaneous cytotoxicity against SP2 and MBL2&nbsp; mouse tumoral cells.Recently, we discovered a sea star Igkappa gene with immune properties. This gene was inserted in a CMV(cytomegalovirus)&nbsp; and finally in a plasmid called «&nbsp;young&nbsp;» plasmid. </em></p> <p><em>The induced«&nbsp;young&nbsp;» protein exerted a spontaneous cytotoxicity against osteosarcom cells (U2oS cells) against A-375&nbsp; melanome cells and Hela cells</em></p> Michel Leclerc Copyright (c) 2021 Michel Leclerc https://creativecommons.org/licenses/by/4.0 2021-11-06 2021-11-06 3 1 49 51 10.46545/aijcs.v3i1.220