Physical Properties of Cyclestructure

Abstract Azo – cyclic derivatives are a part from a ring that has more than type of atoms. Nitrogen, oxygen and sulfur are often found along with carbon in heterocycles rings. Heterocycles derivatives are common in chemical chemistry, and many have fulfilled important physiological active in plant and animal kingdoms and have an important biological properties, such as, the antibiotic penicillin, sedative phenabarbital, and sugar replacing reagent saccharin, all having heterocycles ring.

The great number of reactions undergone by azonium salts may be divided into two classes: replacement, in which nitrogen is lost as N 2 , and some other atom or group becomes attached to the ring in its place; and coupling, in which the nitrogen is retained in the product, to yield product of the general formula (Ar-N=N-Ar'), called azo compounds. (6)veral methods have been used to synthesize azo compounds, such as (7)(8)(9) : (i) oxidation of hydrazine derivatives by HgO , or urea derivatives using t-butylhypochlorite (ii) Reaction of diazonium salt with phenols in the presence of NaOH at 0 ºC .These methods seem to be the best because of the high yield of the azo compounds.
Diazonium coupling is one of the main route for the synthesis of sulfa drugs, such as sulfanoamide, which has many therapeutic applications (10) .Some new azo sulfa drugs were synthesized by Abdel Hafeez and coworkers (11) .

Triazoles
In five-membered ring systems, the presence of three nitrogen heteroatoms defines an interesting class of compounds, called triazoles which may be of two types; the 1,2,3-triazole (I) and the 1,2,4-triazoles (II) (13) .The former is originally called vicinal (vic) triazoles and the latter symmetrical (sym) triazoles.
The 1,2,3-triazole unit is an important element in a number of drugs and development candidates.The triazole is a structural backbone of many antibiotics, antiallergics, antimetastasis agents and antidepressants (15) .Their synthesis usually started with azides which are considered a very important compounds due to their industrial as well as biological applications.
Organic azides are generally safe compounds, those of low molecular weights can be unstable and, therefore, difficult to handle (16) .
The chemistry of azides has thus attracted the attention of many chemists, since many of these compounds play an important role in organic chemistry.